High Quality Lysolecithin Liquid (Lysophosphatidylcholines )
Lysophosphatidylcholines (LPC, lysoPC), also called lysolecithins, are a class of chemical compounds which are derived from phosphatidylcholines. They result from partial hydrolysis of phosphatidylcholines, which removes one of the fatty acid groups. The hydrolysis is generally the result of the enzymatic action of phospholipase A2. Among other properties, they stimulate phagocyte recruitment when released by apoptotic cells. Moreover, LPCs can be used in the lab to cause demyelination of brain slices, to mimic the effects of demyelinating diseases such as multiple sclerosis. Further, they are known to stimulate phagocytosis of the myelin sheath and can change the surface properties of erythrocytes. LPC-induced demyelination is thought to occur through the actions of recruited macrophages and microglia which phagocytose nearby myelin. Invading T cells are also thought to mediate this process. Bacteria such as Legionella pneumophila utilize phospholipase A2 end-products ( fatty acids and lysophospholipids) to cause host cell (macrophage) apoptosis through cytochrome C release.
High Quality Lysolecithin Liquid (Lysophosphatidylcholines ) Specification
|Light Yellow to brown Viscous liquid
|White soybean and inoffensive odor
|Acetone Insoluble %
|Loss on Drying W/%
|Acid Value mg/g
|Peroxide Value meq/kg
|Heavy Metal(As Pb) mg/kg
|Solvent Residue mg/kg
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